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 PubMed
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4. Creating Subject Searches

There are three steps in the construction of a subject search.

1. MeSH search
2. Keyword search
3. Combine with Boolean 'OR' operator

MeSH (Medical Subject Headings) terms attempt to encompass all of the concepts of medicine, within a hierarchical classification system, currently employing more than 31,000 terms. Medline articles are indexed by at least one, and normally several MeSH terms. All decent Medline interfaces must provide a means of translating your search into equivalent MeSH terms, and also to allow you to choose whether you want just the MeSH term itself, or to also include some or all of its 'children' in the MeSH hierarchy (called exploding a MeSH term). MeSH terms are also refined by the use of Sub Headings which are broad concepts which cut across the MeSH hierarchical tree - examples include Genetics, Epidemiology, Drug Therapy.

The creation of a subject search will be covered in more detail when we look at the PubMed and Ovid interfaces, and there is only a brief description below.

PubMed performs a combined MeSH match and textword search for you automatically - for example, if you type multiple sclerosis into the search box, PubMed runs the search "Multiple sclerosis"[MeSH Terms] OR Multiple sclerosis[Text Word]. Note that the MeSH term is automatically exploded in PubMed.

The Ovid interface allows you to combine MeSH mapping and textword searches on its Mapping Display page. If you select the MeSH term multiple sclerosis, with Explode enabled, together with the .mp option, this produces a search of the form exp Multiple sclerosis/ or "multiple sclerosis".mp which is a close equivalent to the PubMed search.

Once you have created your subject search, you combine it with the appropriate systematic search, using the Boolean AND operator, to answer the clinical question.