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PubMed Advanced Interface - I. Starting

PubMed will perform a combined MeSH match and textword search for you automatically. As an example we will work through a search for articles on the treatment of multiple sclerosis.

When you enter a term in the search box, PubMed attempts to match it to a MeSH (Medical Subject Headings) term. If it fails to find a match it will then try to match your term to a Journal name, a Phrase List, and an Author name. The MeSH mapping process actually checks for a MeSH match, then a Subheadings match, and finally a search for equivalent terms using the Unified Medical Language System (UMLS).

In addition, provided a match is found, PubMed will also perform a search for your term as a textword. e.g. "Multiple sclerosis"[MeSH Terms] OR Multiple sclerosis[Text Word]. Note also, that PubMed automatically explodes the MeSH term (i.e. it includes the term and all of its children in the MeSH hierarchy), and you would have to use syntax such as "Multiple sclerosis"[MH:NOEXP] to prevent this.

Type in a search string, in this case 'multiple sclerosis' and press 'Preview/Index'. If you press Go then PubMed will execute the search and display results, but at this stage we are still building our search, so we would normally want to use the Preview screen first.

Figure 1. PubMed Main Search Screen

PubMed

You will be taken to the Preview/Index Page, which is where you can systematically construct searches using Boolean operators - press the Preview button on this screen. You will see the number of references you have retrieved with your search.